Health Insights

X-linked hypophosphatemia (XLH) is a rare, progressive, genetic disease caused by mutations in the PHEX gene. The disease is characterized by low levels of phosphate — an important mineral for the formation of healthy bones and teeth — in the blood. Although there is currently no…

X-linked hypophosphatemia (XLH) is a rare, progressive genetic disease in which excess phosphate is excreted by the kidneys, resulting in low levels of the mineral in the blood. Phosphate is essential for healthy bones and teeth. People with XLH have rickets-like symptoms such as osteomalacia (soft…

X-linked hypophosphatemia (XLH) is a genetic disease characterized by weak bones and teeth that are fragile and easily broken. Some types of exercise can place too much stress on your bones and joints if you have XLH, so you should take extra care when exercising and engaging in sports.

X-linked hypophosphatemia (XLH) is a rare X-linked genetic disease characterized by low levels of phosphate in the blood, and is caused by a mutation in the PHEX gene. This gene influences the activity of a protein called FGF23, which is responsible for regulating the reabsorption of phosphate…

X-linked hypophosphatemia (XLH) is a genetic disease caused by mutations in a gene called PHEX. These mutations lead to excessive amounts of a protein called FGF23. High FGF23 levels cause the body to lose phosphate in urine, instead of retaining it. This drop in the amount of…